AN IN SILICO HIGH-THROUGHPUT SCREEN IDENTIFIES POTENTIAL SELECTIVE INHIBITORS FOR THE NON-RECEPTOR TYROSINE KINASE PYK2

An in silico high-throughput screen identifies potential selective inhibitors for the non-receptor tyrosine kinase Pyk2

Tomer Meirson, Abraham O Samson, Hava Gil-Henn Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel Abstract: The non-receptor sweet life carts tyrosine kinase proline-rich tyrosine kinase 2 (Pyk2) is a critical mediator of signaling from cell surface growth factor and adhesion receptors to cell migration, proliferation, and survi

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